New Boston virus

Please share this video, this research must STOP. Gain of function research in the USA today using enhanced potential pandemic pathogen (ePPP) research <br> <br>Professor Shmuel Shapira, lead scientist, Israeli Government <br> <br>https://www.dailymail.co.uk/he....alth/article-1132367 <br> <br>This should be totally forbidden, it's playing with fire <br> <br>Dr Richard Ebright, Rutgers University, New Brunswick <br> <br>The research is a clear example of gain of function research. <br> <br>If we are to avoid a next lab-generated pandemic, <br> <br>it is imperative that oversight of enhanced potential pandemic pathogen research be strengthened. <br> <br>it is imperative that officials at US-government agencies, <br> <br>who repeatedly have placed the public at risk by repeatedly violating the existing policies be held accountable <br> <br>Prof David Livermore, microbiology, University of East Anglia <br> <br>given the strong likelihood that the Covid pandemic originated from the escape of a lab-manipulated coronavirus in Wuhan, <br> <br>these experiments seem profoundly unwise <br> <br>Boston University's National Emerging Infectious Diseases Laboratories is one of 13 biosafety level 4 labs in the US <br> <br>Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron <br> <br>14th October 2022 <br> <br>Boston University School of Medicine <br> <br>https://www.biorxiv.org/conten....t/10.1101/2022.10.13 <br> <br>Predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, <br> <br>even in fully vaccinated individuals, <br> <br>and causes attenuated disease compared with other major viral variants recognized to date <br> <br>The Omicron spike (S) protein, unusually large number of mutations, <br> <br>is considered the major driver of these phenotypes <br> <br>We generated chimeric recombinant SARS-CoV-2 <br> <br>A chimera or chimeric virus <br> <br>One virus containing genetic material derived from two or more distinct viruses <br> <br>US Center for Veterinary Biologics <br> <br>https://www.aphis.usda.gov/ani....mal_health/vet_biolo <br> <br>A new hybrid microorganism, <br> <br>created by joining nucleic acid fragments from two or more different microorganisms, <br> <br>in which each of at least two of the fragments, <br> <br>contain essential genes necessary for replication <br> <br>We generated chimeric recombinant SARS-CoV-2 <br> <br>Encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate, <br> <br>and compared this virus with the naturally circulating Omicron variant. <br> <br>The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, <br> <br>mainly due to mutations in the receptor-binding motif, <br> <br>yet unlike naturally occurring Omicron, <br> <br>efficiently replicates in cell lines and primary-like distal lung cells. <br> <br>In K18-hACE2 mice <br> <br>https://www.jax.org/strain/034860 <br> <br>K18-hACE2 transgenic mice express human ACE2, <br> <br>including airway epithelia where infections typically begin. <br> <br>Because K18-hACE2 are susceptible to SARS-CoV-2 and SARS-CoV viruses, they are useful for studying antiviral therapies to COVID-19 and SARS. <br> <br>In K18-hACE2 mice <br> <br>Omicron causes mild, non-fatal infection, <br> <br>the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. <br> <br>This indicates that while the vaccine escape of Omicron is defined by mutations in S, <br> <br>major determinants of viral pathogenicity reside outside of S. <br> <br>Frankenstein, Mary Shelley, 1818 <br> <br>Frightful must it be; for supremely frightful would be the effect of any human endeavour to mock the stupendous mechanism of the Creator of the world (1831 edition)